How cannabis and alcohol together affect impairment

The Impact of Cannabis Route of Administration and Co-Administration of Alcohol on Impairment

NIH-funded research Johns Hopkins University · NIH-11097260

This study is looking at how using cannabis in different ways—like smoking, eating, or vaping—affects your ability to think and react when you also drink alcohol, so we can better understand the risks for people who drive or work while using these substances.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11097260 on NIH RePORTER

What this research studies

This research investigates how different methods of consuming cannabis, such as smoking, eating, or vaping, affect impairment when combined with alcohol. It aims to understand the acute effects of these substances on psychomotor skills, attention, and cognitive functioning, which are crucial for safe driving and workplace performance. The study will involve human participants in controlled laboratory settings, using rigorous methods to ensure reliable results. By comparing the effects of cannabis consumed in various forms alongside alcohol, the research seeks to provide insights into the risks associated with their concurrent use.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who use cannabis and alcohol, particularly those who may consume them together.

Not a fit: Patients who do not use cannabis or alcohol, or those with severe cognitive impairments that prevent them from participating in the study, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better guidelines and interventions to reduce accidents and improve safety for individuals who use cannabis and alcohol.

How similar studies have performed: Previous studies have shown significant impairment effects from cannabis and alcohol, but this research is novel in its focus on different cannabis consumption methods.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.