NIH-funded research R21 grant

How cannabidiol (CBD) interacts with cancer treatments

Official title: Interaction of cannabidiol (CBD) with targeted inhibitors of essential cancer signaling pathways

Funded at Research Inst of Fox Chase Can Ctr · NIH-10813799 · Data updated 2026-11-12

This study is looking at how cannabidiol (CBD) might affect the way cancer treatments, like chemotherapy, work for patients, especially those using CBD for pain relief or other benefits during their treatment.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionResearch Inst of Fox Chase Can Ctr
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startApril 1, 2023
Project endMarch 31, 2026
Funding year2024
Award (this year)$199,821
NIH project number5R21CA280446-02
Project IDNIH-10813799 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with advanced cancers who are considering or currently using CBD as part of their treatment regimen.

Less likely to help

Patients who are not using CBD or are not undergoing systemic cancer therapies may not benefit from this research.

What this research studies

This research investigates the effects of cannabidiol (CBD) on the effectiveness of various cancer therapies, including chemotherapy and targeted treatments. It aims to understand how CBD may influence patient responses to these therapies and the factors that contribute to resistance against treatment. By examining the interaction between CBD and cancer signaling pathways, the study seeks to provide insights that could help tailor cancer treatments to individual patients. Patients using CBD for pain relief or perceived benefits during cancer treatment may find this research particularly relevant.

Why it matters

Potential benefit: If successful, this research could lead to improved cancer treatment strategies that enhance the effectiveness of therapies for patients using CBD.

How similar studies have gone: While there is growing evidence supporting the interaction of CBD with cancer therapies, this research explores a relatively novel hypothesis that has not been extensively tested.

Where this research is happening

  • Research Inst of Fox Chase Can Ctr
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Golemis, Erica a. — Research Inst of Fox Chase Can Ctr
  • Study coordinator: Golemis, Erica a.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.