How cancer cells survive stress and starvation
Regulated cell death and responses to starvation in cancer
This study is looking at how cancer cells stay alive even when they don’t have enough nutrients, with the hope of finding new ways to make cancer treatments work better for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906027 on NIH RePORTER |
What this research studies
This research investigates how cancer cells manage to survive in stressful environments, such as during nutrient starvation. By understanding the mechanisms that allow these cells to avoid death, researchers aim to identify new targets for cancer therapies. The study employs advanced imaging techniques and cell biological approaches to explore the regulation of cell death and the adaptive responses of cancer cells. This could lead to innovative strategies for enhancing the effectiveness of cancer treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer who may benefit from novel therapeutic approaches.
Not a fit: Patients with non-cancerous conditions or those whose cancer is already in an advanced stage with limited treatment options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new cancer therapies that more effectively target and eliminate cancer cells.
How similar studies have performed: Previous research has shown promise in understanding cell death mechanisms in cancer, indicating that this approach could yield significant insights.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Overholtzer, Michael H. — Sloan-Kettering Inst Can Research
- Study coordinator: Overholtzer, Michael H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.