How cancer cells control protein production and its treatment implications
Mechanisms of regulated translation control in cancer and its therapeutic implications
This study is looking at how cancer cells change the way they make proteins to help them grow and survive, with the hope of finding new ways to treat cancer that could help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10891508 on NIH RePORTER |
What this research studies
This research investigates how cancer cells manipulate their protein production machinery to promote their growth and survival. By using advanced genetic models and quantitative measures, the team aims to uncover specific interactions that can be targeted for therapy. The research focuses on understanding the role of certain proteins in cancer development and how these insights can lead to new treatment strategies. Patients may benefit from findings that identify new therapeutic targets or strategies to combat cancer more effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer who may benefit from novel therapeutic approaches.
Not a fit: Patients with non-cancerous conditions or those who do not have a genetic predisposition to cancer may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies that improve treatment outcomes for cancer patients.
How similar studies have performed: Other research has shown promising results in targeting translational control mechanisms in cancer, indicating that this approach has potential for success.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Ruggero, Davide — University of California, San Francisco
- Study coordinator: Ruggero, Davide
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.