How cancer can affect the heart and blood vessels
The role of cancer in cardiovascular disease
This project looks at whether having cancer can directly cause heart disease and how people with both conditions might be treated.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11323492 on NIH RePORTER |
What this research studies
Researchers will combine genetic studies, specialized animal models, and large collections of human tissue and clinical records to look for links between cancer and heart disease. They will apply machine-learning tools to clinical and molecular data to find patterns that traditional studies missed. The team will test possible causal mechanisms in transgenic animals and compare those findings with signals from human biospecimens. Participation could involve sharing medical records or allowing use of stored samples through Stanford or partner sites.
Who could benefit from this research
Good fit: People with a history of cancer—especially those treated with chemotherapy or radiation—or people living with both cancer and cardiovascular disease are the most relevant candidates.
Not a fit: People without any history of cancer or cardiovascular risk factors are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this work could reveal causes and new treatment strategies to prevent or reduce heart disease in people with cancer.
How similar studies have performed: Prior observational studies have suggested links but were limited by confounding, and this combined genetics/animal/AI approach is newer and less previously tested.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Leeper, Nicholas James — Stanford University
- Study coordinator: Leeper, Nicholas James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.