How caloric restriction affects aging in monkeys
Molecular Networks in Aging and Caloric Restriction in Rhesus Monkeys
This study is looking at how eating fewer calories (without being unhealthy) might help Rhesus monkeys live longer and healthier lives, which could give us helpful ideas for promoting better aging in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11004652 on NIH RePORTER |
What this research studies
This research investigates the effects of caloric restriction on aging and age-related diseases in Rhesus monkeys. By examining molecular changes and metabolic pathways, the study aims to understand how reducing calorie intake without malnutrition can improve health and longevity. The research involves detailed profiling of cellular mechanisms and interactions that occur during aging and caloric restriction, potentially revealing new insights into the biology of aging. Patients may benefit from the findings as they could lead to new strategies for promoting healthy aging.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are older adults, particularly those aged 65 and above, who are interested in strategies to improve their health as they age.
Not a fit: Patients who are younger than 65 years old or those who are not interested in dietary interventions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into dietary interventions that enhance healthspan and reduce the risk of age-related diseases in humans.
How similar studies have performed: Previous research has shown promising results regarding caloric restriction and its effects on aging in various species, suggesting that this approach may yield valuable insights in humans as well.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Anderson, Rozalyn M. — University of Wisconsin-Madison
- Study coordinator: Anderson, Rozalyn M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.