How Calcium Affects Brain Communication
Calcium control of Neurotransmitter Release
This research explores how calcium helps brain cells talk to each other, a process vital for learning and memory.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11092223 on NIH RePORTER |
What this research studies
Our brain cells communicate by sending tiny chemical messages called neurotransmitters, which are essential for everything from thinking to remembering. This communication relies on a precise dance involving calcium, which acts like a switch to release these messages. When this process doesn't work correctly, it can contribute to various brain conditions. This project aims to understand exactly how calcium controls these messages at a very detailed level, hoping to uncover new ways to help people with neurological disorders.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation, but its findings are relevant to individuals living with neurological disorders affecting brain communication, learning, and memory.
Not a fit: Patients whose conditions are unrelated to brain cell communication or calcium signaling may not directly benefit from this specific line of basic research.
Why it matters
Potential benefit: Understanding these fundamental mechanisms could pave the way for new treatments for neurological disorders that affect learning and memory.
How similar studies have performed: While much is known about brain cell communication, this project aims to bridge existing knowledge gaps by providing a more comprehensive understanding of calcium's precise role.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Krishnakumar, Shyam S — Yale University
- Study coordinator: Krishnakumar, Shyam S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.