How brain signals affect alcohol-related behavior

Cortical-noradrenaline signaling in alcohol behavioral engagement

NIH-funded research Indiana University Indianapolis · NIH-10930952

This study is looking at how certain parts of the brain affect drinking behavior by watching how mice interact with alcohol, which could help us understand more about why people drink.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-10930952 on NIH RePORTER

What this research studies

This research investigates how specific brain circuits influence behavior related to alcohol consumption. Using advanced techniques, researchers will measure brain activity while observing how mice engage with alcohol in a controlled setting. The study focuses on the Locus Coeruleus and its connection to the anterior cingulate cortex and anterior insula, aiming to understand how these areas regulate responses to alcohol. By analyzing neural activity patterns, the research seeks to uncover the mechanisms behind alcohol-related behaviors.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals struggling with alcohol use or those interested in understanding the neurological factors influencing alcohol consumption.

Not a fit: Patients who do not consume alcohol or have no interest in alcohol-related behaviors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new insights into the brain mechanisms that drive alcohol consumption, potentially informing treatment strategies for alcohol use disorders.

How similar studies have performed: Previous research has shown promising results in understanding brain signaling related to substance use, suggesting that this approach could yield valuable insights.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.