NIH-funded research R01 grant

How brain networks help us learn from rewards

Official title: Functional architecture of striatal networks in cue-reward learning

Funded at University of Minnesota · NIH-10973190 · Data updated 2026-11-12

This study is looking at how our brains learn from rewards and make decisions, especially how we move from thinking about our choices to doing things automatically, and it's designed to help people who struggle with learning and motivation.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startJanuary 1, 2023
Project endOctober 31, 2027
Funding year2025
Award (this year)$507,484
NIH project number5R01MH129370-03
Project IDNIH-10973190 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing difficulties with learning, motivation, or cognitive functions.

Less likely to help

Patients with stable cognitive functions and no learning or motivational impairments may not benefit from this research.

What this research studies

This research investigates the brain's mesocorticostriatal network, which plays a crucial role in how we learn from rewards and make decisions. It focuses on understanding the transition from goal-directed actions to automatic behaviors as learning progresses. By using innovative techniques, the study aims to explore how different brain circuits communicate during this learning process, particularly how information flows through specific pathways in the brain. This could provide insights into conditions where learning and motivation are impaired.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for disorders related to learning and motivation, such as addiction or depression.

How similar studies have gone: Previous research has shown promising results in understanding brain networks related to learning, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Saunders, Benjamin Thomas — University of Minnesota
  • Study coordinator: Saunders, Benjamin Thomas

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.