How brain networks control inflammation in the body
Official title: Brain neural networks regulating inflammation
Funded at Feinstein Institute for Medical Research · NIH-10930885 · Data updated 2026-11-12
This study is exploring how nerves send signals about inflammation to the brain and how the brain helps manage that inflammation, with the goal of finding new treatments for conditions like arthritis, colitis, and anxiety that could help patients feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $612,326 |
| NIH project number | 5R01AR083159-02 |
| Project ID | NIH-10930885 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals suffering from conditions like arthritis, colitis, anxiety, or other inflammation-related disorders.
✕Less likely to help
Patients with non-inflammatory conditions or those not affected by the diseases being studied may not benefit from this research.
What this research studies
This research investigates how sensory neurons communicate inflammation signals to the brain and how the brain regulates the body's inflammatory response. It utilizes advanced techniques like optogenetics and pharmacogenetics to map and manipulate specific brain neural networks involved in inflammation. By understanding these pathways, the research aims to uncover new ways to control inflammation-related conditions such as arthritis, colitis, and anxiety. Patients may benefit from insights that could lead to innovative treatments targeting these neural pathways.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively manage inflammation-related diseases.
How similar studies have gone: Previous research has shown promising results in understanding the brain's role in regulating inflammation, suggesting that this approach could lead to significant advancements.
Where this research is happening
-
Feinstein Institute for Medical Research
Manhasset, United States Active
Researchers
- Principal investigator: Tracey, Kevin J — Feinstein Institute for Medical Research
- Study coordinator: Tracey, Kevin J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.