How brain network disruptions affect obesity in people with schizophrenia

Triple-network connectivity contributions to obesity in Schizophrenia

['FUNDING_FELLOWSHIP'] · UNIVERSITY OF COLORADO DENVER · NIH-10994516

This study is looking at how changes in brain connections might affect weight gain in people with schizophrenia, especially when they see food, to help find better ways to manage obesity linked to their treatment.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO DENVER (nih funded)
Locations1 site (Aurora, UNITED STATES)
Trial IDNIH-10994516 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between brain network disruptions and obesity in individuals with schizophrenia. By using functional magnetic resonance imaging (fMRI), the study will measure brain connectivity in participants while they are at rest and when exposed to food cues. The goal is to understand how these disruptions contribute to increased obesity risk, which is a significant health concern for those with schizophrenia. The findings could lead to better-targeted treatments for managing weight gain associated with antipsychotic medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia who are experiencing obesity or weight gain.

Not a fit: Patients without a diagnosis of schizophrenia or those who are not experiencing obesity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for obesity in patients with schizophrenia, potentially reducing their risk of related health issues.

How similar studies have performed: Previous research has shown that understanding brain connectivity can provide insights into obesity, suggesting that this approach may yield valuable findings.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers, Cardiovascular Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.