How brain circuits help us learn complex vocal behaviors
Corticostriatal contributions to motor exploration and reinforcement
['FUNDING_R01'] · DUKE UNIVERSITY · NIH-10928116
This study is looking at how certain brain circuits help us learn to speak and make music, and it's for anyone interested in understanding how we change our voices based on what we hear and learn.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10928116 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specific brain circuits in learning complex vocal behaviors, such as speech and musical expression. By monitoring and manipulating the activity of neurons in the corticostriatal circuits, the study aims to understand how these circuits contribute to motor exploration and reinforcement learning. The researchers will use advanced imaging techniques and optogenetic methods to explore the relationship between vocal variability and neural activity, providing insights into how we adapt our vocalizations based on feedback. This approach combines experimental neuroscience with computational modeling to enhance our understanding of vocal learning.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who are experiencing difficulties with vocalization or motor skills.
Not a fit: Patients who do not have any vocal or motor learning challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for individuals with speech and motor disorders.
How similar studies have performed: Previous research has shown success in understanding simpler motor learning tasks, but this investigation into complex vocal behaviors is relatively novel.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOONEY, RICHARD D — DUKE UNIVERSITY
- Study coordinator: MOONEY, RICHARD D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.