How brain circuits control heart health during stress

Cortical-Medullary Circuitry Preventing the Cardiovascular Consequences of Chronic Stress

['FUNDING_R01'] · COLORADO STATE UNIVERSITY · NIH-10748415

This study looks at how the brain helps keep your heart healthy when you're under stress, and it aims to find ways to protect your heart from the negative effects of long-term stress.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCOLORADO STATE UNIVERSITY (nih funded)
Locations1 site (FORT COLLINS, UNITED STATES)
Trial IDNIH-10748415 on ClinicalTrials.gov

What this research studies

This research investigates the brain's role in managing cardiovascular health in response to chronic stress. It focuses on specific brain circuits that help regulate the body's stress responses, particularly how they influence blood pressure and heart function. By studying these neural mechanisms in animal models, the research aims to uncover how certain brain cells can prevent harmful cardiovascular effects caused by prolonged stress. The findings could lead to new strategies for protecting heart health in stressed individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing high levels of chronic stress who are at risk for cardiovascular diseases.

Not a fit: Patients who do not experience chronic stress or have pre-existing severe cardiovascular conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that help prevent cardiovascular diseases linked to chronic stress.

How similar studies have performed: Other research has shown promising results in understanding the brain's influence on cardiovascular health, suggesting that this approach could yield valuable insights.

Where this research is happening

FORT COLLINS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: cardiovascular disorder, Cardiovascular Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.