How brain circuits control eating and dopamine levels

Cerebellar-striatal circuits for control of dopamine activity and food intake

NIH-funded research Scintillon Institute for Photobiology · NIH-11074589

This study is looking at how certain brain areas help control our eating habits and feelings of reward when we eat, which could help us find new ways to treat eating disorders and obesity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionScintillon Institute for Photobiology NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-11074589 on NIH RePORTER

What this research studies

This research investigates the role of specific brain circuits, particularly those involving the cerebellum and striatum, in regulating food intake and dopamine activity. By studying unique neurons activated during eating, the research aims to understand how these neurons influence appetite and the brain's reward system. The approach includes advanced techniques to analyze neuronal activity and its effects on food consumption and metabolic responses. Patients may benefit from insights into how these brain mechanisms can be targeted to address eating disorders and obesity.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals struggling with obesity or appetite disorders who may benefit from understanding the neurological basis of their condition.

Not a fit: Patients who do not have issues related to food intake or obesity may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for obesity and appetite disorders by targeting brain circuits that control eating behavior.

How similar studies have performed: Previous research has shown promising results in understanding brain mechanisms related to appetite control, suggesting that this approach could yield valuable insights.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Appetite Disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.