How brain circuits affect stress coping and alcohol use
Corticolimbic circuitry in adaptive stress coping behavior and subsequent alcohol drinking
['FUNDING_OTHER'] · UNIVERSITY OF NEW MEXICO · NIH-11088538
This study looks at how people with PTSD handle stress and how that might lead them to drink alcohol, focusing on specific parts of the brain that could help us find better ways to support coping strategies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEW MEXICO (nih funded) |
| Locations | 1 site (ALBUQUERQUE, UNITED STATES) |
| Trial ID | NIH-11088538 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between stress coping mechanisms and alcohol consumption in individuals with post-traumatic stress disorder (PTSD). It focuses on understanding how certain brain regions, particularly the prelimbic cortex and the basolateral amygdala, influence coping strategies and subsequent alcohol use. By using an animal model, the study examines how variations in brain signaling can affect stress responses and drinking behavior, with the goal of identifying potential therapeutic targets for improving coping strategies. The research employs advanced techniques to manipulate brain circuits and assess their impact on behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from PTSD, particularly those who may struggle with alcohol use as a coping mechanism.
Not a fit: Patients who do not have PTSD or do not engage in alcohol consumption as a coping strategy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help individuals with PTSD manage their symptoms and reduce alcohol consumption.
How similar studies have performed: Previous research has shown promising results in understanding the brain mechanisms involved in stress and alcohol use, suggesting that this approach could yield valuable insights.
Where this research is happening
ALBUQUERQUE, UNITED STATES
- UNIVERSITY OF NEW MEXICO — ALBUQUERQUE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ORNELAS, LAURA C. — UNIVERSITY OF NEW MEXICO
- Study coordinator: ORNELAS, LAURA C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.