How brain cells interact to influence learned movements
Astrocyte-Neuron Circuits Underlying Cortical Mechanisms of Learned Behavior
This study is looking at how special brain cells called astrocytes help our brain learn new movements, like when you practice a sport or a dance, and it's designed for anyone interested in understanding how our brains work during learning.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10908366 on NIH RePORTER |
What this research studies
This research investigates the role of astrocytes, a type of brain cell, in the motor cortex and how they interact with neurons during the learning of voluntary movements. By using advanced imaging techniques, the study aims to understand how astrocytes contribute to synaptic plasticity and neuronal dynamics as mice learn specific movements. The research will explore the mechanisms by which astrocytes modulate synaptic transmission and their response to neuronal activity, providing insights into the cellular processes underlying learned behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions affecting motor function or learning, such as stroke survivors or those with neurodegenerative diseases.
Not a fit: Patients with purely psychological conditions unrelated to motor function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing motor learning and recovery in patients with movement disorders.
How similar studies have performed: Previous research has shown promising results in understanding the role of astrocytes in brain function, suggesting that this approach could yield valuable insights.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Sur, Mriganka — Massachusetts Institute of Technology
- Study coordinator: Sur, Mriganka
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.