How brain cells affect blood pressure regulation in response to shift work
Official title: The Role of Astrocytes in Circadian Control of Blood Pressure in the Nucleus of the Solitary Tract
Funded at Rowan University · NIH-11074547 · Data updated 2026-11-12
This study is looking at how certain brain cells called astrocytes might affect blood pressure in people who work different shifts, especially since changing work hours can mess with our body's natural clock and lead to heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rowan University NIH-funded |
| Lab location | 1 site (Glassboro, United States) |
| Project start | April 15, 2024 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $150,000 |
| NIH project number | 5R16GM153695-02 |
| Project ID | NIH-11074547 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who work rotating shifts and are experiencing issues related to blood pressure regulation.
✕Less likely to help
Patients who do not work shift hours or have no blood pressure-related health concerns may not benefit from this research.
What this research studies
This research investigates the role of astrocytes, a type of brain cell, in regulating blood pressure, particularly in individuals who work rotating shifts. It explores how circadian misalignment, caused by irregular work hours, can lead to cardiovascular issues such as high blood pressure. By examining the nucleus of the solitary tract, a key area in the brain that integrates signals related to blood pressure, the study aims to understand the biological mechanisms behind these health problems. The research will utilize animal models to analyze the interactions between astrocytes and neurons in this region.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing blood pressure and reducing cardiovascular risks in shift workers.
How similar studies have gone: While the specific focus on astrocytes in this context is novel, previous studies have shown that addressing circadian misalignment can improve cardiovascular health outcomes.
Where this research is happening
-
Rowan University
Glassboro, United States Active
Researchers
- Principal investigator: Martinez, Diana — Rowan University
- Study coordinator: Martinez, Diana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.