How brain cells adapt during learning and memory processes
Official title: Mechanisms of compartmentalized plasticity in learning and memory
Funded at University of Iowa · NIH-11045030 · Data updated 2026-11-12
This study is looking at how our experiences shape the way our brains process information, using fruit flies to learn more about how memories are made and how they affect our choices and actions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $388,750 |
| NIH project number | 5R01NS124716-03 |
| Project ID | NIH-11045030 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in the biological mechanisms of learning and memory, particularly those affected by memory disorders.
✕Less likely to help
Patients with conditions unrelated to memory or learning processes may not benefit from this research.
What this research studies
This research investigates how experiences influence the way information is processed in the brain, focusing on the plasticity of neurons at a subcellular level. By studying the nervous system of fruit flies, the researchers aim to understand how different signals are integrated during learning events, which could affect decision-making and behavior. The project will explore the mechanisms of plasticity in specific brain regions that are responsible for processing olfactory memories. This approach allows for a detailed examination of how memories are formed and how they influence actions.
Why it matters
Potential benefit: If successful, this research could lead to new insights into memory formation and potential treatments for memory-related disorders.
How similar studies have gone: Previous research has shown promising results in understanding neuronal plasticity, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Tomchik, Seth M — University of Iowa
- Study coordinator: Tomchik, Seth M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.