How brain arousal and hormones affect eating disorders in young girls

General Brain Arousal and Risk for Eating Disorder

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10872278

This study is looking at how hormonal changes during early teenage years affect brain development and the chances of binge eating disorders, especially in girls, to see how boys and girls might be different in this regard.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10872278 on ClinicalTrials.gov

What this research studies

This research investigates how hormonal changes during early adolescence influence brain development and the risk of binge eating disorders, particularly in girls. It aims to understand the differences between boys and girls in their susceptibility to these disorders by examining the role of gonadal hormones on brain networks related to arousal, reward, and emotional control. The study will involve both baseline assessments and a two-year follow-up to track changes over time, using advanced computational models to analyze the data.

Who could benefit from this research

Good fit: Ideal candidates for participation are girls aged 10 to 13 who are in the early stages of adolescence.

Not a fit: Boys or individuals outside the specified age range may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for eating disorders in young girls.

How similar studies have performed: Previous research has shown promising results in understanding hormonal influences on behavior, making this approach both relevant and potentially impactful.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.