How brain activity influences impulsive decision-making

The role of distributional reinforcement learning in human neurons during impulsive choices

['FUNDING_R01'] · UNIVERSITY OF UTAH · NIH-11009899

This study looks at how our brain cells help us make quick decisions about rewards, especially when we're feeling impulsive, and it's designed for people who are having brain surgery so researchers can see how their brains work during these choices.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF UTAH (nih funded)
Locations1 site (SALT LAKE CITY, UNITED STATES)
Trial IDNIH-11009899 on ClinicalTrials.gov

What this research studies

This research investigates how human neurons encode information about potential rewards when making impulsive choices. By studying brain activity in neurosurgical patients, the team aims to identify specific brain areas involved in decision-making processes. The research utilizes tasks designed to simulate real-life choices, allowing researchers to observe how the brain's reinforcement learning mechanisms operate in real-time. The findings could provide insights into the neural basis of impulse control and related disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation are individuals undergoing neurosurgery who can provide insights into brain activity related to decision-making.

Not a fit: Patients with no history of impulsive behavior or substance use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for impulse control and substance use disorders.

How similar studies have performed: Other research has shown promising results in understanding neural mechanisms of decision-making, suggesting that this approach could yield valuable insights.

Where this research is happening

SALT LAKE CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.