How body composition affects survival in breast cancer patients
Official title: Body composition and breast cancer survival: immune and metabolic biomarkers in breast tumors
Funded at Kaiser Foundation Research Institute · NIH-10873125 · Data updated 2026-11-12
This study is looking at how having low muscle and extra fat might affect breast cancer survival and treatment outcomes, and it aims to help create better, personalized therapies for breast cancer patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | July 1, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $100,924 |
| NIH project number | 5R01CA251589-05 |
| Project ID | NIH-10873125 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer patients who have low muscle mass or excess adiposity.
✕Less likely to help
Patients with normal body composition and no metabolic syndrome may not benefit from this research.
What this research studies
This research investigates the relationship between body composition, specifically low muscle mass and excess fat, and breast cancer survival. It aims to understand how these factors influence the immune response and metabolic pathways in breast tumors. By studying human breast cancer patients, the research seeks to uncover how adverse body composition may lead to worse treatment outcomes and increased risk of recurrence. The study will analyze immune responses and signaling pathways to develop personalized therapies for breast cancer patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better survival rates for breast cancer patients with adverse body composition.
How similar studies have gone: Other research has shown promising results in understanding the impact of body composition on cancer outcomes, suggesting this approach could yield valuable insights.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Feliciano, Elizabeth Marjorie Cespedes — Kaiser Foundation Research Institute
- Study coordinator: Feliciano, Elizabeth Marjorie Cespedes
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.