How blood pressure medications affect heart and kidney health in chronic kidney disease
Official title: Assessment of the Impact of antihypertensive Medications on vascular and renal outcomes in Chronic Kidney Disease (AIM-CKD)
Funded at Case Western Reserve University · NIH-11125843 · Data updated 2026-11-12
This study is looking at how blood pressure medications affect the heart and kidneys in people with chronic kidney disease, to help understand how these treatments can improve health and reduce risks over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $641,016 |
| NIH project number | 5R01HL175410-02 |
| Project ID | NIH-11125843 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with chronic kidney disease.
✕Less likely to help
Patients with acute kidney injury or those not on antihypertensive medications may not benefit from this research.
What this research studies
This research investigates the effects of antihypertensive medications on heart and kidney health in patients with chronic kidney disease (CKD). By analyzing data from large studies, the research aims to understand how these medications can influence cardiovascular risks and kidney function. The study will utilize advanced statistical methods to address the complexities of real-world data, including varying treatment regimens and the risk of death. Patients may be monitored over time to assess the long-term impacts of these medications on their health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance heart and kidney health for patients with chronic kidney disease.
How similar studies have gone: Previous research has shown promising results in understanding the effects of antihypertensive medications on cardiovascular health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Wang, Ming — Case Western Reserve University
- Study coordinator: Wang, Ming
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.