How blood pressure medications affect heart and kidney health in chronic kidney disease

Assessment of the Impact of antihypertensive Medications on vascular and renal outcomes in Chronic Kidney Disease (AIM-CKD)

NIH-funded research Case Western Reserve University · NIH-11125843

This study is looking at how blood pressure medications affect the heart and kidneys in people with chronic kidney disease, to help understand how these treatments can improve health and reduce risks over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11125843 on NIH RePORTER

What this research studies

This research investigates the effects of antihypertensive medications on heart and kidney health in patients with chronic kidney disease (CKD). By analyzing data from large studies, the research aims to understand how these medications can influence cardiovascular risks and kidney function. The study will utilize advanced statistical methods to address the complexities of real-world data, including varying treatment regimens and the risk of death. Patients may be monitored over time to assess the long-term impacts of these medications on their health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with chronic kidney disease.

Not a fit: Patients with acute kidney injury or those not on antihypertensive medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that enhance heart and kidney health for patients with chronic kidney disease.

How similar studies have performed: Previous research has shown promising results in understanding the effects of antihypertensive medications on cardiovascular health, suggesting that this approach could yield valuable insights.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.