How blood glycoproteins are regulated by lectin receptors in health and disease
Official title: Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease
Funded at Sanford Burnham Prebys Medical Discovery Institute · NIH-11063251 · Data updated 2026-11-12
This study is looking at how certain receptors in your body help manage important proteins in your blood, which can affect your health, especially if you have autoimmune diseases or autism spectrum disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanford Burnham Prebys Medical Discovery Institute NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $487,500 |
| NIH project number | 5R01HL158677-03 |
| Project ID | NIH-11063251 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with autoimmune diseases or autism spectrum disorders.
✕Less likely to help
Patients with conditions unrelated to blood glycoprotein regulation may not receive any benefit from this research.
What this research studies
This research investigates the role of lectin receptors in regulating blood glycoproteins, which are crucial for understanding health and disease. The study focuses on how these receptors interact with glycoproteins in the blood, influencing their abundance and function. By examining the mechanisms that control the half-lives of these proteins, the research aims to uncover how changes in glycoprotein levels can be linked to various diseases. Patients may benefit from insights into how their blood composition relates to health conditions, particularly autoimmune diseases and autism spectrum disorders.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and treatments for conditions linked to blood glycoprotein abnormalities.
How similar studies have gone: Other research has shown promise in understanding glycoprotein interactions, but this specific approach to studying lectin receptors is relatively novel.
Where this research is happening
-
Sanford Burnham Prebys Medical Discovery Institute
La Jolla, United States Active
Researchers
- Principal investigator: Marth, Jamey — Sanford Burnham Prebys Medical Discovery Institute
- Study coordinator: Marth, Jamey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.