How blood energy levels relate to muscle function and aging
The relationship between blood based bioenergetics and muscle function, mobility, and aging
This study is looking at how the energy production in your blood cells impacts your muscle strength and movement as you get older, and it hopes to find signs that can help predict when physical performance might decline, so we can help older adults stay active and mobile.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10992159 on NIH RePORTER |
What this research studies
This research investigates how energy production in blood cells affects muscle function and mobility as people age. It aims to identify biomarkers that can predict declines in physical performance, which is crucial for developing interventions to maintain mobility in older adults. The study utilizes advanced techniques to measure bioenergetic function in blood cells, linking these findings to overall physical ability. By understanding the relationship between blood-based bioenergetics and muscle function, the research seeks to uncover new insights into age-related mobility decline.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing mobility issues or declines in physical performance.
Not a fit: Patients who are younger and do not have any mobility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preserving mobility and improving quality of life in older adults.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial dysfunction and its impact on physical performance, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Shiva, Sruti — University of Pittsburgh at Pittsburgh
- Study coordinator: Shiva, Sruti
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.