How blood clotting affects liver scarring
Novel mechanisms linking blood coagulation to liver fibrosis
This study is looking at how certain proteins in your blood that help with clotting might affect liver damage and scarring, with the hope of finding new ways to treat liver diseases for people like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11207318 on NIH RePORTER |
What this research studies
This research investigates the role of blood coagulation factors in the signaling processes that occur during liver injury and inflammation. It aims to understand how the activation of specific receptors by blood clotting proteins can lead to liver scarring, a condition known as hepatic fibrosis. By exploring the mechanisms involved, the research seeks to uncover new insights that could lead to better treatments for liver diseases. Patients may benefit from this research as it could identify new therapeutic targets for managing liver fibrosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic liver injury or conditions that may lead to liver fibrosis.
Not a fit: Patients with acute liver injury or those without any liver-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent or reduce liver scarring in patients with liver diseases.
How similar studies have performed: Other research has shown promising results in understanding the role of blood coagulation in liver diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Poole, Lauren G — Rutgers Biomedical and Health Sciences
- Study coordinator: Poole, Lauren G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.