How biological clocks affect cell behavior and health.
Circadian Regulation of Cellular Homeostasis
This study looks at how our body's natural clocks affect important functions like metabolism and hormone release, and how problems with these rhythms might lead to health issues like sleep disorders and cancer, with the hope that understanding these patterns in mice can help us learn more about how they impact our health and disease risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m Agrilife Research NIH-funded |
| Lab location | 1 site (College Station, UNITED STATES) |
| Project ID | NIH-11001100 on NIH RePORTER |
What this research studies
This research investigates the role of biological clocks in regulating various bodily functions, including metabolism and hormone release, and how disruptions to these rhythms can lead to health issues like sleep disorders and cancer. By studying the mouse mammary gland, the research aims to understand how circadian rhythms influence stem and progenitor cell behavior, particularly during development. The approach includes examining how these clocks shift from regulating daily activities to supporting developmental processes, which could have implications for understanding cancer progression. Patients may benefit from insights into how their biological rhythms affect their health and disease risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults who experience disruptions in their circadian rhythms, such as shift workers or those with sleep disorders.
Not a fit: Patients who do not have any circadian rhythm disruptions or related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating conditions related to circadian rhythm disruptions, such as certain cancers.
How similar studies have performed: Other research has shown promising results in understanding the impact of circadian rhythms on health, suggesting that this approach could yield valuable insights.
Where this research is happening
College Station, UNITED STATES
- Texas A&m Agrilife Research — College Station, United States (Active)
Researchers
- Principal investigator: Porter, Weston W — Texas A&m Agrilife Research
- Study coordinator: Porter, Weston W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.