How bacteria use vitamin B12 and its relatives to interact in communities
Bacterial Corrinoid Metabolism Across Scales: From Molecular Specificity to Community Dynamics
This study looks at how tiny organisms in our bodies, like bacteria, use important nutrients called corrinoids, including vitamin B12, and how they work together, which could help us find new ways to improve our health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11037901 on NIH RePORTER |
What this research studies
This research investigates how microbial communities, including those in the human body, utilize a group of metabolites known as corrinoids, which include vitamin B12. By examining the complex interactions among different bacterial species, the study aims to understand how these bacteria share and utilize corrinoids for their metabolic processes. The research employs advanced biochemical techniques to analyze the structural diversity of corrinoids and their role in microbial interactions. This could lead to insights into how manipulating these interactions might benefit human health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with gut microbiome-related health issues or those interested in the effects of diet on microbial health.
Not a fit: Patients who do not have any gastrointestinal issues or are not interested in microbiome research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of microbial health and lead to new strategies for improving gut health and treating related conditions.
How similar studies have performed: Previous research has shown promising results in understanding microbial interactions through the study of metabolites, indicating potential for success in this area.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Taga, Michiko E. — University of California Berkeley
- Study coordinator: Taga, Michiko E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.