How bacteria organize their DNA
Investigating regulators of bacterial chromosome organization
This research helps us understand how bacteria pack their genetic material, which could lead to new ways to fight infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11143038 on NIH RePORTER |
What this research studies
Bacteria are tiny, but their DNA is very long and must be carefully folded to fit inside their cells. We want to learn the secrets of how bacteria organize their DNA, especially how it coils and what proteins help structure it. By understanding these processes, we hope to find new weaknesses in bacteria. This knowledge could help us develop new medicines to treat bacterial infections more effectively.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation but aims to benefit anyone affected by bacterial infections in the future.
Not a fit: Patients seeking immediate treatment options for bacterial infections will not directly benefit from this early-stage laboratory research.
Why it matters
Potential benefit: If successful, this work could uncover new targets for developing much-needed antibiotics to combat bacterial infections.
How similar studies have performed: This work builds on recent discoveries by the researchers, addressing challenges where previous tools and knowledge were limited.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Guo, Monica S. — University of Washington
- Study coordinator: Guo, Monica S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.