How bacteria in the gut interact and affect each other's growth
Contact-dependent interbacterial responses modulate intestinal colonization by Bacteroides species
This study is looking at how different types of Bacteroides bacteria in our gut work together and compete with each other, which could help us understand how to improve gut health and develop new treatments.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-11101121 on NIH RePORTER |
What this research studies
This research investigates how different species of Bacteroides bacteria in the human gut interact with each other and how these interactions influence their ability to colonize the intestines. By using advanced proteomics technology, the study aims to uncover the molecular mechanisms behind these interactions, particularly focusing on how bacteria can compete and adapt to their environment. The research will utilize a gnotobiotic mouse model to translate these findings into potential therapeutic applications for gut health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with gastrointestinal conditions or those interested in gut microbiota health.
Not a fit: Patients who do not have any gastrointestinal issues or are not interested in gut microbiome research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for manipulating gut bacteria to improve intestinal health and treat related diseases.
How similar studies have performed: Other research has shown promising results in understanding bacterial interactions in the gut, suggesting that this approach could yield valuable insights.
Where this research is happening
Iowa City, United States
- University of Iowa — Iowa City, United States (Active)
Researchers
- Principal investigator: Bosch, Dustin E — University of Iowa
- Study coordinator: Bosch, Dustin E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.