How bacteria help Coxsackievirus infections
Bacterial-mediated enhancement of Coxsackievirus
This study is looking at how certain bacteria might help the Coxsackievirus, which can make people sick, spread and survive better, and it's aimed at finding new ways to prevent and treat these infections in both kids and adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10923577 on NIH RePORTER |
What this research studies
This research investigates how certain bacteria can enhance the infectivity and stability of Coxsackievirus, which causes various diseases in both children and adults. By using a mouse model, the study aims to identify specific bacterial components that interact with the virus and understand the mechanisms behind this interaction. The researchers will focus on the cell wall components of bacteria like Salmonella to determine how they affect the virus's ability to replicate and cause disease. This could lead to new insights into prevention and treatment strategies for Coxsackievirus infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adults who are at risk for Coxsackievirus infections or have experienced related health issues.
Not a fit: Patients who do not have a history of Coxsackievirus infections or are not at risk for such infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new methods for preventing and treating Coxsackievirus infections, potentially reducing the incidence of related diseases.
How similar studies have performed: While the specific approach of using bacterial interactions to enhance Coxsackievirus understanding is novel, related research has shown that bacterial components can influence viral behavior.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Robinson, Christopher Michael — Indiana University Indianapolis
- Study coordinator: Robinson, Christopher Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.