How bacteria help Coxsackievirus infections
Bacterial-mediated enhancement of Coxsackievirus
This study is looking at how certain bacteria might help the Coxsackievirus, which can cause illnesses like myocarditis and hand, foot, and mouth disease, become more infectious and stable, with the hope of finding new ways to prevent and treat these infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10864959 on NIH RePORTER |
What this research studies
This research investigates the role of specific bacteria in enhancing the infectivity and stability of Coxsackievirus, which can cause serious illnesses like myocarditis and hand, foot, and mouth disease. Using a mouse model, the study aims to identify the bacterial components that interact with the virus and understand the mechanisms behind this interaction. By examining how certain bacteria, such as Salmonella, influence the virus's ability to replicate and survive, the research seeks to uncover potential targets for new treatments. Patients may benefit from insights that could lead to better prevention and management strategies for Coxsackievirus infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adults who are at risk of or currently experiencing Coxsackievirus infections.
Not a fit: Patients with other viral infections not related to Coxsackievirus may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from Coxsackievirus infections.
How similar studies have performed: While the specific approach of using bacteria to enhance Coxsackievirus research is novel, similar studies have shown that understanding virus-bacteria interactions can lead to significant advancements in treatment.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Robinson, Christopher Michael — Indiana University Indianapolis
- Study coordinator: Robinson, Christopher Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.