How bacteria affect healing in the larynx after injury
Microbial modulation of mucosal wound healing in the larynx
['FUNDING_R21'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11053543
This study is looking at how bacteria in the throat can help heal injuries like surgery or trauma, and it aims to find ways to improve recovery for people with voice problems.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11053543 on ClinicalTrials.gov |
What this research studies
This research investigates the role of bacteria in the healing process of the larynx after injuries such as surgery or trauma. By studying the microbial communities present in the larynx, the researchers aim to understand how these bacteria can influence inflammation and tissue regeneration. The study will utilize a specialized model to observe the healing stages and measure the impact of different bacterial species on the recovery of laryngeal tissue. Patients with voice disorders may benefit from insights gained about how to improve healing and reduce complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing voice disorders due to laryngeal injuries or inflammation.
Not a fit: Patients with voice disorders not related to laryngeal injuries or those with chronic conditions unrelated to bacterial influence may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for voice disorders by enhancing mucosal healing in the larynx.
How similar studies have performed: While research on the laryngeal microbiome is limited, similar studies in other mucosal systems have shown promising results in understanding microbial roles in healing.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AN, RAN — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: AN, RAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bacterial disease treatment, bacterial infectious disease treatment