How antibiotics affect gut health and weight gain
Relating impacts of antibiotics on the gut metabolome and microbiome to host physiology and weight
This study looks at how taking antibiotics might change the bacteria in your gut and affect your metabolism, which could lead to weight gain, helping people understand how their antibiotic use might impact their weight and health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-10932679 on NIH RePORTER |
What this research studies
This research investigates the relationship between antibiotic use and its effects on the gut microbiome and metabolism, particularly in relation to obesity. It focuses on understanding how antibiotics disrupt the gut microbiome and alter the metabolic environment, potentially leading to weight gain. By studying these impacts in both humans and animal models, the research aims to uncover the mechanisms behind antibiotic-associated obesity. Patients may gain insights into how their antibiotic use could affect their weight and overall health.
Who could benefit from this research
Good fit: Ideal candidates include individuals who have recently used antibiotics and are experiencing weight changes or metabolic issues.
Not a fit: Patients who have not used antibiotics or do not have concerns related to weight or metabolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of obesity linked to antibiotic use.
How similar studies have performed: Previous research has indicated a link between antibiotic use and obesity, suggesting that this approach has potential for significant findings.
Where this research is happening
Providence, United States
- Brown University — Providence, United States (Active)
Researchers
- Principal investigator: Belenky, Peter — Brown University
- Study coordinator: Belenky, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.