How anti-viral T cells move and respond in the bloodstream
Intravascular Immune Surveillance by Anti-viral T Cells
['FUNDING_R01'] · HARVARD MEDICAL SCHOOL · NIH-10975937
This study is looking at how special immune cells called CD8 T cells move through the blood to help fight infections and tumors, and it’s for anyone interested in understanding how these cells work better against viruses.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD MEDICAL SCHOOL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10975937 on ClinicalTrials.gov |
What this research studies
This research investigates the behavior of CD8 T cells, which are crucial for fighting off infections and tumors. It focuses on how these immune cells migrate through the bloodstream to find and interact with viral antigens. By using advanced imaging techniques, the study aims to understand the different types of T cells that develop in response to viral infections and how they function in various tissues. The goal is to uncover the mechanisms that dictate their movement and effectiveness in combating diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with viral infections or certain types of cancers who may benefit from enhanced immune responses.
Not a fit: Patients with autoimmune diseases or those who do not have viral infections or cancers may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing immune responses against viral infections and cancers.
How similar studies have performed: Previous research has shown promising results in understanding T cell behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- HARVARD MEDICAL SCHOOL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VON ANDRIAN, ULRICH H — HARVARD MEDICAL SCHOOL
- Study coordinator: VON ANDRIAN, ULRICH H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.