How alcohol use in the teen years affects the brain into adulthood

National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative Resource

NIH-funded research University of California, San Diego · NIH-11112536

Following teens and young adults to track how early alcohol use affects their brain, thinking, sleep, and daily activity.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11112536 on NIH RePORTER

What this research studies

This consortium follows a community sample recruited at ages 12–21 and now tracks participants into young adulthood to see how alcohol use relates to brain and behavior. Participants complete yearly brain scans (MRI, DTI, fMRI), cognitive and clinical tests, questionnaires, and sometimes remote visits through a mobile app. New work adds advanced imaging plus sleep and physical activity tracking with wearables to better capture daily-life effects. A coordinating center at UCSD organizes data across five U.S. sites so researchers can link drinking patterns to changes from adolescence into the 20s and early 30s.

Who could benefit from this research

Good fit: Ideal participants are adolescents and young adults (originally recruited at ages 12–21 and currently followed into their late 20s/early 30s) who are willing to undergo brain scans, cognitive testing, and periodic follow-up in person or remotely.

Not a fit: People outside the study's age range or those seeking immediate clinical treatment for alcohol use disorder rather than research participation are unlikely to gain direct benefit from joining.

Why it matters

Potential benefit: If successful, this work could pinpoint early brain changes tied to teen drinking to guide prevention and targeted treatment for young people at risk.

How similar studies have performed: Other long-term imaging cohorts have successfully linked adolescent drinking patterns with brain and cognitive differences, so this continues an established research approach.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.