How alcohol use affects fear responses in veterans with PTSD

Neural correlates of fear conditioning and extinction in veterans with PTSD and alcohol use disorder

NIH-funded research VA San Diego Healthcare System · NIH-11070362

This study looks at how drinking alcohol affects the way veterans with PTSD learn to cope with fear and trauma, hoping to find better ways to help them recover from both their PTSD and alcohol use.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-11070362 on NIH RePORTER

What this research studies

This research investigates the impact of alcohol use on fear extinction and contextual fear processing in veterans suffering from PTSD and alcohol use disorders. It aims to understand how current alcohol consumption influences the recovery processes from trauma, particularly focusing on the brain regions involved in fear responses. By examining these relationships, the study seeks to identify critical mechanisms that could inform more effective treatment strategies for veterans facing these dual challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with PTSD who also have issues with alcohol use.

Not a fit: Patients without PTSD or those who do not have alcohol use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment approaches for veterans with PTSD and alcohol use disorders, enhancing their recovery outcomes.

How similar studies have performed: Previous research has shown that understanding the interplay between alcohol use and PTSD recovery is crucial, but this specific approach is relatively novel and untested.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.