How alcohol affects the gut-brain connection in multiple sclerosis
Alcohol's Impact on the Gut-Brain Axis in a Mouse Model of Multiple Sclerosis
This study is looking at how drinking alcohol might affect inflammation in the brain and gut for people with multiple sclerosis (MS), using mice to help us understand how different amounts of alcohol could influence MS symptoms and overall health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project ID | NIH-10893367 on NIH RePORTER |
What this research studies
This research investigates the effects of alcohol on neuroinflammation using a mouse model of multiple sclerosis (MS). The study aims to understand how different doses of alcohol influence the gut-brain axis and immune responses related to MS. By integrating expertise in neuroimmunology, bioinformatics, and microbiome research, the research seeks to uncover the complex interactions between alcohol consumption and MS progression. The findings could provide insights into how dietary factors, like alcohol, impact the health of individuals with MS.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who consume alcohol.
Not a fit: Patients without a diagnosis of multiple sclerosis or those who do not consume alcohol may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of alcohol consumption in patients with multiple sclerosis.
How similar studies have performed: While the specific focus on alcohol's impact on the gut-brain axis in MS is novel, related research has shown that dietary factors can significantly influence autoimmune diseases.
Where this research is happening
Austin, United States
- University of Texas at Austin — Austin, United States (Active)
Researchers
- Principal investigator: Melamed, Esther — University of Texas at Austin
- Study coordinator: Melamed, Esther
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.