How alcohol affects the body's muscle clock and its role in muscle disease
Alcohol and the skeletal muscle clock
This study is looking at how drinking alcohol affects the body's muscle clock and could lead to muscle problems, with the goal of finding new ways to help people who struggle with muscle weakness from alcohol use.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project ID | NIH-11058231 on NIH RePORTER |
What this research studies
This research investigates the impact of alcohol on the skeletal muscle's internal clock and its potential link to alcohol-associated muscle disease (AAMD). It aims to understand how alcohol disrupts the molecular mechanisms that regulate muscle function, leading to weakness and reduced quality of life. By exploring these pathways, the research seeks to identify new therapeutic targets that could help mitigate the effects of alcohol on muscle health. Patients may benefit from insights that could lead to improved treatments for muscle-related issues caused by alcohol consumption.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old who have experienced muscle weakness or functional decline related to alcohol use.
Not a fit: Patients who do not consume alcohol or have no history of alcohol-related muscle issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve muscle health and quality of life for individuals affected by alcohol-related muscle diseases.
How similar studies have performed: While the specific approach of targeting the skeletal muscle clock in relation to alcohol is novel, previous research has shown that understanding molecular mechanisms can lead to significant advancements in treatment.
Where this research is happening
Tallahassee, United States
- Florida State University — Tallahassee, United States (Active)
Researchers
- Principal investigator: Steiner, Jennifer Lynn — Florida State University
- Study coordinator: Steiner, Jennifer Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.