How alcohol affects TB risk and long-term lung health in people living with HIV
Administrative Core
This project looks at whether and how alcohol use changes the chances of getting TB and having lasting lung problems for people living with HIV, using ongoing patient groups in Uganda.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11146587 on NIH RePORTER |
What this research studies
If you take part, researchers will follow people living with HIV over time at clinics in Uganda and record alcohol use, TB infections, treatments, and lung health. Staff will collect health information, medical tests, and follow-up data to see who develops TB or long-term lung damage after TB treatment. The center combines two linked research projects and a data/biostatistics team to make sure results are reliable. An administrative core coordinates the work, manages the teams, and helps share findings that could affect care.
Who could benefit from this research
Good fit: Adults living with HIV, especially those receiving care at participating clinics in Uganda and with different levels of alcohol use or TB history, are the ideal candidates.
Not a fit: People without HIV, those not exposed to TB, or those unable to attend the participating clinics in Uganda are unlikely to directly benefit from joining this project.
Why it matters
Potential benefit: If successful, this work could help reduce TB illness and lasting lung problems among people with HIV by guiding prevention and follow-up care related to alcohol use.
How similar studies have performed: Previous research has linked alcohol to worse TB and HIV outcomes, but this program's combined long-term cohort and lung-health follow-up in Uganda builds on and expands earlier findings.
Where this research is happening
Boston, United States
- Boston Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Samet, Jeffrey H. — Boston Medical Center
- Study coordinator: Samet, Jeffrey H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.