How alcohol affects lung and liver health in people with HIV
Official title: Alcohol metabolism potentiates HIV-induced lung and liver multimorbidity via inter-organ crosstalk
Funded at Emory University · NIH-11085643 · Data updated 2026-11-12
This study is looking at how drinking alcohol might affect the health of people living with HIV, especially how it could make lung and liver problems worse, so we can find better ways to help manage their overall health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $148,449 |
| NIH project number | 1K99AA032220-01 |
| Project ID | NIH-11085643 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who consume alcohol and may be experiencing or at risk for lung and liver complications.
✕Less likely to help
Patients who do not have HIV or those who do not consume alcohol may not benefit from this research.
What this research studies
This research investigates the impact of alcohol consumption on the health of individuals living with HIV, particularly focusing on how alcohol may worsen lung and liver conditions. The study aims to understand the mechanisms by which alcohol metabolism influences the release of extracellular vesicles from the lungs, which may then affect liver function and contribute to chronic diseases. By examining the interplay between HIV, alcohol, and organ health, the research seeks to uncover new insights into managing multimorbidity in patients with HIV.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing lung and liver health in individuals with HIV, potentially reducing the burden of multimorbidity.
How similar studies have gone: Previous research has indicated that alcohol can exacerbate health issues in individuals with HIV, suggesting that this study builds on established findings rather than exploring a completely novel approach.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: New-Aaron, Moses O — Emory University
- Study coordinator: New-Aaron, Moses O
Related research
Other NIH-funded projects on the same topics.
-
Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
-
M-CaRE: Mobile clinics and a smart heart-lung care tool for multimorbidity
A mobile, multilingual tool plus community health workers will help screen and manage high blood pressure and COPD in diverse adult patients, especially in underserved areas.
-
Alcohol and HIV interaction driving lung and liver damage through cell signals
This program explores how alcohol worsens lung and liver problems in people with HIV by affecting cell signals that travel between organs.
-
Addressing heart disease risk with HIV care in Nigeria
A plan to bring heart-disease prevention and treatment into HIV care for people living with HIV in Nigeria.
-
Understanding how care teams connect to better care for older adults with ADRD and multiple health problems
This grant tests how the way clinicians work together (their network) affects care quality and outcomes for older adults with Alzheimer's or related dementias and multiple health issues.
-
MADIVA: Using digital tools to study multimorbidity in Africa
A hosted research program in Africa is building advanced data resources and language-model based tools to study how multiple diseases and aging affect people in rural South Africa and urban Kenya.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.