How alcohol affects liver and heart energy levels and function
The effects of alcohol metabolism on hepatic and cardiac energy state and function
This study looks at how drinking alcohol affects the way your liver and heart produce energy, helping us understand how it can lead to health issues like fatty liver and heart problems, and it’s designed for people who want to learn more about the impact of their alcohol use on their overall health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10908544 on NIH RePORTER |
What this research studies
This research investigates how the metabolism of alcohol impacts energy production and function in the liver and heart. It focuses on the biochemical processes involved in alcohol breakdown, particularly how it alters the balance of important molecules that are crucial for energy metabolism. By examining the effects of alcohol on liver function and its subsequent impact on heart health, the study aims to uncover the mechanisms that lead to conditions like alcoholic fatty liver disease and alcoholic cardiomyopathy. Patients may be involved in understanding how their alcohol consumption affects their overall metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who consume alcohol regularly and may be experiencing symptoms related to liver or heart dysfunction.
Not a fit: Patients who do not consume alcohol or have no liver or heart-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from alcohol-related liver and heart diseases.
How similar studies have performed: Previous research has shown that understanding the metabolic effects of alcohol can lead to significant insights into liver and heart diseases, indicating that this approach has potential for success.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Fletcher, Justin — Ut Southwestern Medical Center
- Study coordinator: Fletcher, Justin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.