How alcohol affects cocaine use in monkeys
The effect of ethanol self-administration on cocaine reinforcement in male and female monkeys
['FUNDING_FELLOWSHIP'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11059594
This study looks at how drinking alcohol might make cocaine more addictive in male and female monkeys, helping us understand why some people with cocaine use problems also drink, and what this could mean for better treatments.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-11059594 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between alcohol consumption and cocaine reinforcement in male and female monkeys. By using animal models, the study aims to understand how ethanol may enhance the effects of cocaine, potentially leading to more severe addiction and poorer treatment outcomes. The research will explore the mechanisms behind the co-use of these substances, which is common among individuals with cocaine use disorder. The findings could help bridge the gap between preclinical and clinical research on substance use disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of cocaine use disorder who also consume alcohol.
Not a fit: Patients who do not have a history of substance use disorders or who only use cocaine or alcohol in isolation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals struggling with cocaine use disorder, particularly those who also consume alcohol.
How similar studies have performed: While the co-use of alcohol and cocaine has been documented, this specific approach to understanding their interaction in a controlled setting is relatively novel and has not been extensively tested.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALLEN, MIA ISABEL — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: ALLEN, MIA ISABEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.