How alcohol affects brain development in children
Ethanol-induced disruption of kinase signaling pathways in brain development
This study looks at how drinking alcohol can affect brain development in children, especially how it messes with important signals in the brain, and it aims to find ways to help kids who might be struggling because of this.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Upstate Medical University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project ID | NIH-10910111 on NIH RePORTER |
What this research studies
This research investigates the impact of alcohol exposure on brain development in children, particularly focusing on how it disrupts signaling pathways that are crucial for proper brain function. The study examines the effects of acute ethanol exposure on specific proteins involved in brain signaling, aiming to identify common molecular mechanisms that lead to developmental issues such as intellectual disability. By understanding these mechanisms, the research seeks to inform potential neuroprotective strategies and improve outcomes for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been exposed to alcohol in utero and may be experiencing developmental challenges.
Not a fit: Patients who have not been exposed to alcohol during pregnancy or who are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for children affected by fetal alcohol syndrome and related developmental disorders.
How similar studies have performed: Previous research has shown success in identifying molecular mechanisms related to alcohol exposure and brain development, suggesting that this approach could yield valuable insights.
Where this research is happening
Syracuse, United States
- Upstate Medical University — Syracuse, United States (Active)
Researchers
- Principal investigator: Olson, Eric Christopher — Upstate Medical University
- Study coordinator: Olson, Eric Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.