How alcohol affects bone health in humans and monkeys
Effects of alcohol on bone remodeling balance in male and female non-human primates and humans
This study looks at how drinking a lot of alcohol affects bone health in both people and monkeys, hoping to find ways to help those at risk of fractures because of their drinking habits.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project ID | NIH-11036963 on NIH RePORTER |
What this research studies
This research investigates the impact of chronic heavy alcohol consumption on bone quality and remodeling in both male and female non-human primates and humans. By using rhesus macaques, which share physiological similarities with humans, the study aims to understand how alcohol affects bone density and the repair processes of bones. The researchers will compare the bone responses of these primates to those of humans to identify potential interventions for alcohol-related bone issues. The findings could help in developing targeted treatments for individuals at risk of fractures due to alcohol consumption.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged and elderly individuals, particularly those with a history of heavy alcohol consumption.
Not a fit: Patients who do not consume alcohol or have no history of alcohol-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing fractures in individuals who consume alcohol heavily.
How similar studies have performed: Previous research has indicated that alcohol negatively impacts bone health, but this study aims to provide more detailed insights by comparing findings in both primates and humans.
Where this research is happening
Corvallis, United States
- Oregon State University — Corvallis, United States (Active)
Researchers
- Principal investigator: Iwaniec, Urszula T — Oregon State University
- Study coordinator: Iwaniec, Urszula T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.