How alcohol affects aggression and impulsive behavior in the brain

Aggression and SEIP: Neural Correlates During Alcohol Intoxication

NIH-funded research Ohio State University · NIH-10476608

This study is looking at how alcohol affects aggressive and impulsive behaviors and how people with Alcohol Use Disorder respond to social threats, using brain scans to see what happens in the brain, so if you have a history of drinking and acting impulsively, your participation could help us understand this connection better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-10476608 on NIH RePORTER

What this research studies

This research investigates the impact of alcohol on aggressive and impulsive behaviors, as well as how individuals process social-emotional threats. By using advanced imaging techniques like functional MRI, the study aims to understand the neural mechanisms behind these behaviors in individuals with Alcohol Use Disorder and a history of impulsive aggression. Participants will be grouped based on their alcohol use and aggression history to explore how these factors influence brain responses to threats. The findings could provide insights into the complex relationship between alcohol consumption and aggression.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a history of Alcohol Use Disorder and impulsive aggressive behavior, as well as healthy controls without these conditions.

Not a fit: Patients who do not have a history of alcohol use or aggression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals struggling with Alcohol Use Disorder and related aggressive behaviors.

How similar studies have performed: Previous research has shown promising results in understanding the neural correlates of aggression and alcohol use, suggesting that this approach could yield valuable insights.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.