How air pollution affects women's reproductive health during their menstrual cycle and early pregnancy

Impacts of Acute Ambient Air Pollution Exposure on Women's Reproductive Health: Identifying Mechanisms and Susceptible Reproductive Processes Across the Menstrual Cycle and Early Pregnancy

['FUNDING_R21'] · UNIVERSITY OF MASSACHUSETTS AMHERST · NIH-10829447

This study is looking at how short-term exposure to air pollution might affect women's reproductive health, especially during important times like their menstrual cycle and early pregnancy, to help understand any challenges it may cause for those trying to conceive.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MASSACHUSETTS AMHERST (nih funded)
Locations1 site (HADLEY, UNITED STATES)
Trial IDNIH-10829447 on ClinicalTrials.gov

What this research studies

This research investigates the effects of acute exposure to ambient air pollution on women's reproductive health, particularly during critical periods such as the menstrual cycle and early pregnancy. By analyzing data from a previous study involving women trying to conceive, the researchers aim to identify how air pollution may alter inflammatory responses and lead to reproductive challenges. The study will utilize advanced air quality models to assess participants' exposure to various pollutants and their potential impact on fertility and pregnancy outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who are planning to conceive or are in the early stages of pregnancy, particularly those living in areas with varying levels of air pollution.

Not a fit: Patients who are not planning to conceive or are not in the reproductive age range may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and strategies to mitigate the negative effects of air pollution on women's reproductive health.

How similar studies have performed: Previous research has shown associations between air pollution and fertility, but this study aims to refine understanding of specific reproductive processes affected, making it a novel approach.

Where this research is happening

HADLEY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.