How air pollution affects pregnancy outcomes through placental microRNAs
Particulate air pollution, pregnancy outcomes, and the role of placental extracellular microRNAs
This study is looking at how air pollution might affect pregnancy, especially in terms of preterm births and babies being born smaller than usual, by examining how pollution exposure changes certain molecules in the placenta that could impact both moms and their babies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10898773 on NIH RePORTER |
What this research studies
This research investigates the impact of particulate air pollution on pregnancy outcomes, specifically focusing on preterm birth and low birth weight. It aims to understand how exposure to air pollution during critical windows of pregnancy can alter the expression of microRNAs in the placenta, which may influence maternal and fetal health. By analyzing data from 800 mother-newborn pairs, the study will explore the mechanisms linking air pollution to adverse pregnancy outcomes, potentially revealing new insights into maternal and child health.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals living in urban areas with varying levels of air pollution exposure.
Not a fit: Patients who are not pregnant or those living in areas with low levels of air pollution may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for mitigating the effects of air pollution on pregnancy, ultimately enhancing maternal and child health outcomes.
How similar studies have performed: Previous research has indicated a link between air pollution and adverse pregnancy outcomes, but this specific approach focusing on placental microRNAs is relatively novel.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Cowell, Whitney — New York University School of Medicine
- Study coordinator: Cowell, Whitney
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.