How air pollution affects heart disease and its progression

Air Pollution, Coronary Events and Atherosclerotic Progression in a Susceptible Population

['FUNDING_R01'] · STATE UNIVERSITY OF NEW YORK AT BUFFALO · NIH-11083558

This study is looking at how air pollution might make heart disease worse for people who already have a condition called atherosclerosis, and it involves checking in with some patients over time to see how their health changes.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTATE UNIVERSITY OF NEW YORK AT BUFFALO (nih funded)
Locations1 site (AMHERST, UNITED STATES)
Trial IDNIH-11083558 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between air pollution and the progression of atherosclerosis, a common cause of heart disease. By studying a cohort of 3,500 patients with atherosclerosis in Beijing, the research aims to understand how long-term exposure to air pollutants may accelerate disease progression and lead to coronary events. The study will involve additional clinic visits for a subset of 1,100 patients to gather more detailed information on their health over time. The findings could provide insights into how environmental factors influence heart health, particularly for those already at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with atherosclerosis, particularly those living in areas with high levels of air pollution.

Not a fit: Patients without atherosclerosis or those living in regions with low air pollution may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved public health strategies that reduce the impact of air pollution on heart disease.

How similar studies have performed: Previous research has indicated a link between air pollution and heart disease, suggesting that this study builds on established findings rather than exploring a completely novel area.

Where this research is happening

AMHERST, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.