How air pollution affects childhood mental health through epigenetics
Epigenetics, air pollution, and childhood mental health
This study is looking at how air pollution might affect the mental health of kids and teens, especially in relation to anxiety and depression, by examining changes in their DNA that could make them more vulnerable to these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11110467 on NIH RePORTER |
What this research studies
This research investigates the relationship between air pollution exposure and mental health issues like anxiety and depression in children and adolescents. It focuses on how fine particulate matter and traffic-related air pollution may alter the epigenome, which could lead to increased risks for these mental health disorders. By analyzing DNA methylation changes, the study aims to identify biomarkers that can help pinpoint children who are more susceptible to developing anxiety and depression due to environmental factors. The research employs an epigenome-wide approach to uncover potential mechanisms that have been overlooked in previous studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents aged 0-20 years who live in areas with varying levels of air pollution.
Not a fit: Patients who do not live in polluted environments or who are not experiencing symptoms of anxiety or depression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification and prevention strategies for anxiety and depression in children exposed to air pollution.
How similar studies have performed: Previous research has shown that environmental factors, including air pollution, can impact mental health, but this specific epigenetic approach is relatively novel.
Where this research is happening
Cincinnati, United States
- University of Cincinnati — Cincinnati, United States (Active)
Researchers
- Principal investigator: Brunst, Kelly J — University of Cincinnati
- Study coordinator: Brunst, Kelly J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.