How aging influences cancer progression and treatment response

AGING AS A SELECTIVE PRESSURE THAT DRIVES TUMOR PROGRESSION

NIH-funded research H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11015947

This study is looking at how getting older affects cancer and its treatment, especially for people aged 65 and up, to find better ways to help older adults fight cancer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst NIH-funded
Lab location1 site (Tampa, United States)
Project IDNIH-11015947 on NIH RePORTER

What this research studies

This research investigates the relationship between aging and cancer, focusing on how age affects cancer progression and the effectiveness of anti-cancer therapies. It aims to understand the biological changes that occur in older patients, particularly those aged 65 and above, and how these changes influence tumor behavior and treatment outcomes. By analyzing human serum samples, the research seeks to uncover the metabolic deregulations associated with aging that may contribute to cancer development and progression. The goal is to provide insights that could lead to more effective cancer treatments tailored for older adults.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 65 and older who are diagnosed with cancer.

Not a fit: Patients under the age of 65 or those without a cancer diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cancer treatments specifically designed for older patients, enhancing their chances of recovery and quality of life.

How similar studies have performed: Other research has indicated that understanding the role of aging in cancer can lead to significant advancements in treatment strategies, suggesting that this approach has potential for success.

Where this research is happening

Tampa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.